Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient

http://www.ncbi.nlm.nih.gov/pubmed/?term=PMC2642879

Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient.

Here it was reported that a boy with Ataxia Telangiectasia got a brain tumor from the neural stem cell therapy, which was found four years later. Investigations resulted in the convincement of the researches that the tumor was derived from the transplanted neural stem cells. (This could also happen with other persons). As i remember the boy survived.

With the Conclusions if the Abstract it is stated:

"This is the first report of a human brain tumor complicating neural stem cell therapy. The findings here suggest that neuronal stem/progenitor cells may be involved in gliomagenesis and provide the first example of a donor-derived brain tumor. Further work is urgently needed to assess the safety of these therapies."

The report in full lenght can be read as a free fulltext, link on the upper right after the link to the abstract which is posted here in the forum.

KInd regards,

Akita